BUTHIONINE SULFOXIMINE AND A METALLODRUG FOR THE TREATMENT OF CANCER, HIV OR A RHEUMATIC DISEASE

BUTHIONINE SULFOXIMINE AND A METALLODRUG FOR THE TREATMENT OF CANCER, HIV OR A RHEUMATIC DISEASE

There is disclosed buthionine sulfoximine (BSO) for use in a method of treatment of cancer, HIV or a rheumatic disease. The method comprises administering (a) BSO at a dosage of less than or equal to 50mg/kg, and (b) a metallodrug at a clinically-acceptable dosage. L'invention concerne de la bu...

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Hauptverfasser: SHYTAJ, Iart Luca, SAVARINO, Andrea, RATHORE, Shailendra Pratap Singh, PROCOPIO, Francesco
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:There is disclosed buthionine sulfoximine (BSO) for use in a method of treatment of cancer, HIV or a rheumatic disease. The method comprises administering (a) BSO at a dosage of less than or equal to 50mg/kg, and (b) a metallodrug at a clinically-acceptable dosage. L'invention concerne de la buthionine sulfoximine (BSO) destinée à être utilisée dans une méthode de traitement du cancer, du VIH ou d'une maladie rhumatismale. La méthode consiste à administrer (a) de la BSO à une dose inférieure ou égale à 50 mg/kg, et (b) un métallomédicament à une dose cliniquement acceptable.