PYRROLO-AROMATIC HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF

The present invention relates to a pyrrolo-aromatic heterocyclic compound, a preparation method therefor, and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound,...

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Bibliographische Detailangaben
Hauptverfasser:	YIN, Huijun, ZONG, Libin, YANG, Yan, YAN, Xu, TIAN, Weixue, DOU, Haoshuai, ZHENG, Li
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pyrrolo-aromatic heterocyclic compound, a preparation method therefor, and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a BTK kinase inhibitor. The compound and the pharmaceutical composition comprising same can be used for treating diseases associated with BTK kinase activity, such as inflammations, autoimmune disorders, and cancers. The definition of each substituent in formula I is the same as that in the description. La présente invention concerne un composé hétérocyclique pyrrolo-aromatique, son procédé de préparation et son utilisation médicale. La présente invention concerne particulièrement, un composé représenté par la formule I, son procédé de préparation, une composition pharmaceutique comprenant le composé, et l'utilisation du composé en tant qu'inhibiteur de la kinase BTK. Selon l'invention, l