COMPLEX FORMULATION COMPRISING HMG-COA REDUCTASE INHIBITOR AND CLOPIDOGREL

The present invention relates to a complex formulation comprising clopidogrel, an HMG-CoA reductase inhibitor, and a membrane containing a hydrophobic compound. More specifically, the objective of the present invention is to provide a complex formulation comprising clopidogrel and an HMG-CoA reductase inhibitor, the complex formulation for prevention or treatment of cardiovascular diseases, which is excellent in storage stability by preventing degradation of the stability of an HMG-CoA reductase inhibitor. La présente invention concerne une formulation complexe comprenant du clopidogrel, un inhibiteur de la HMG-CoA réductase, et une membrane contenant un composé hydrophobe. Plus particulièrement, l'objet de la présente invention est de fournir une formulation complexe comprenant du clopidogrel et un inhibiteur de la HMG-CoA réductase, la formulation complexe étant destinée à la prévention ou au traitement de maladies cardiovasculaires, qui présente une excellente stabilité au stockage en empêchant la dégradation de la stabilité d'un inhibiteur de la HMG-CoA réductase. 본 발명은 클로피도그렐, HMG-CoA 환원효소 억제제 및 소수성 화합물을 함유한 분리막을 포함하는 복합제제에 관한 것이다. 보다 구체적으로 본 발명의 목적은 클로피도그렐과 HMG-CoA 환원효소 억제제를 포함하는 복합제제에 있어, HMG-CoA 환원효소 억제제의 안정성 저하를 막아 보관안정성이 우수한 심혈관계 질환 예방 또는 치료용 복합제제를 제공하는 것이다.