INJECTABLE SUSPENSIONS

The present invention relates to aseptic suspensions, physically stable and injectable through a 25G needle or thinner, comprising crystalline, non- micronized 3-beta-hydroxy-5-alpha-pregnan-20-one particles, a mixture of acylglycerols and cholesterol, processes for preparing crystalline, non- micro...

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Bibliographische Detailangaben
Hauptverfasser:	BRISANDER, Magnus, NORRLIND, Björn, HORVATH, Karol
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION STEROIDS TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention relates to aseptic suspensions, physically stable and injectable through a 25G needle or thinner, comprising crystalline, non- micronized 3-beta-hydroxy-5-alpha-pregnan-20-one particles, a mixture of acylglycerols and cholesterol, processes for preparing crystalline, non- micronized, 3-beta-hydroxy-5-alpha-pregnan-20-one suitable for such suspensions, as well as methods for manufacturing such suspensions. La présente invention concerne des suspensions aseptiques, physiquement stables et injectables à travers une aiguille de 25G ou plus mince, comprenant des particules cristallines, non micronisées de 3-beta-hydroxy-5-alpha-prégnan-20-one, un mélange d'acylglycérols et de cholestérol, des procédés de préparation de suspensions cristallines, non micronisées, 3-beta-hydroxy-5-alpha-prégnan-20-one appropriées pour de telles suspensions, ainsi que des procédés de préparation de telles suspensions.