MULTISPECIFIC ANTIBODY WITH COMBINATION THERAPY FOR IMMUNO-ONCOLOGY

Multispecific antibody having a binding site for ICOS and a binding site for a second antigen, e.g., an immune checkpoint molecule such as PD-L1. Use of the multispecific antibody in immuno-oncology, including for treatment of solid tumours. L'invention concerne un anticorps multi-spécifique ay...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MCCOURT, Matthew John, VAN KRINKS, Cassandra, DEANTONIO, Cecilia, LEE, E-Chiang, KOSMAC, Miha, GALLAGHER, Thomas, ALI, Mohammed Hanif, SANDY, Nikole, GERMASCHEWSKI, Volker, ARKINSTALL, Stephen John, GILLIES, Stephen Douglas, KIRBY, Ian, CAMPBELL, Jamie Iain, SAINSON, Richard
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Multispecific antibody having a binding site for ICOS and a binding site for a second antigen, e.g., an immune checkpoint molecule such as PD-L1. Use of the multispecific antibody in immuno-oncology, including for treatment of solid tumours. L'invention concerne un anticorps multi-spécifique ayant un site de liaison pour ICOS et un site de liaison pour un second antigène, par exemple, une molécule de point de contrôle immunitaire telle que PD-L1. L'invention concerne également l'utilisation de l'anticorps multi-spécifique en immuno-oncologie, notamment pour le traitement de tumeurs solides.