AMORPHOUS OSIMERTINIB MESYLATE, PROCESSES FOR ITS PREPARATION AND SOLID AMORPHOUS DISPERSIONS THEREOF

AMORPHOUS OSIMERTINIB MESYLATE, PROCESSES FOR ITS PREPARATION AND SOLID AMORPHOUS DISPERSIONS THEREOF

The present disclosure provides amorphous osimertinib mesylate, amorphous solid dispersions of osimertinib mesylate, and processes for the preparation thereof. Amorphous osimertinib mesylate and solid dispersions thereof may be used to prepare pharmaceutical dosage forms. La présente invention conce...

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Bibliographische Detailangaben
Hauptverfasser: INDUKURI, Anjaneyaraju, JETTI, Ramakoteswara Rao, MANDE, Hemant Malhari, BANSODE, Prakash, BOMMAREDDY, Aggi Ramireddy, SHUKLA, Vinay Kumar
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present disclosure provides amorphous osimertinib mesylate, amorphous solid dispersions of osimertinib mesylate, and processes for the preparation thereof. Amorphous osimertinib mesylate and solid dispersions thereof may be used to prepare pharmaceutical dosage forms. La présente invention concerne du mésylate d'osimertinib amorphe, des dispersions solides amorphes du mésylate d'osimertinib, et des procédés pour leur préparation. Le mésylate d'osimertinib amorphe et les dispersions solides de celui-ci peuvent être utilisés pour préparer des formes posologiques pharmaceutiques.