POLYMORPHS AND SOLID DISPERSION OF BETRIXABAN AND METHODS FOR THE PREPARATION THEREOF

An amorphous form of betrixaban maleate and process for the preparation of the same are disclosed. A solid dispersion of amorphous betrixaban maleate with pharmaceutically acceptable excipients and processes for the preparation of the same are also disclosed. Betrixaban base polymorphic forms and pr...

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Hauptverfasser: INDUKURI, Anjaneyaraju, PILLI, Narasimha Murty, JETTI, Ramakoteswara Rao, MANDE, Hemant Malhari, TELAGAMSETTY, Bhaskar Kumar, JAYACHANDRA, Sureshbabu, MUGGU, Chaitanya, KAUSHIK, Vipin Kumar, RAVI, Vijaya Krishna, SINGH, Amit
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creator INDUKURI, Anjaneyaraju
PILLI, Narasimha Murty
JETTI, Ramakoteswara Rao
MANDE, Hemant Malhari
TELAGAMSETTY, Bhaskar Kumar
JAYACHANDRA, Sureshbabu
MUGGU, Chaitanya
KAUSHIK, Vipin Kumar
RAVI, Vijaya Krishna
SINGH, Amit
description An amorphous form of betrixaban maleate and process for the preparation of the same are disclosed. A solid dispersion of amorphous betrixaban maleate with pharmaceutically acceptable excipients and processes for the preparation of the same are also disclosed. Betrixaban base polymorphic forms and processes for preparing the same are also disclosed. L'invention concerne une forme polymorphe du maléate de bétrixaban et sur son procédé de préparation. L'invention concerne également une dispersion solide du polymorphe de maléate de bétrixaban avec des excipients pharmaceutiquement acceptables et leurs procédés de préparation. L'invention concerne également des formes polymorphes de base de bétrixaban et des procédés de préparation de celles-ci.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title POLYMORPHS AND SOLID DISPERSION OF BETRIXABAN AND METHODS FOR THE PREPARATION THEREOF
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