POLYMORPHS AND SOLID DISPERSION OF BETRIXABAN AND METHODS FOR THE PREPARATION THEREOF

An amorphous form of betrixaban maleate and process for the preparation of the same are disclosed. A solid dispersion of amorphous betrixaban maleate with pharmaceutically acceptable excipients and processes for the preparation of the same are also disclosed. Betrixaban base polymorphic forms and pr...

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Bibliographische Detailangaben
Hauptverfasser:	INDUKURI, Anjaneyaraju, PILLI, Narasimha Murty, JETTI, Ramakoteswara Rao, MANDE, Hemant Malhari, TELAGAMSETTY, Bhaskar Kumar, JAYACHANDRA, Sureshbabu, MUGGU, Chaitanya, KAUSHIK, Vipin Kumar, RAVI, Vijaya Krishna, SINGH, Amit
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	An amorphous form of betrixaban maleate and process for the preparation of the same are disclosed. A solid dispersion of amorphous betrixaban maleate with pharmaceutically acceptable excipients and processes for the preparation of the same are also disclosed. Betrixaban base polymorphic forms and processes for preparing the same are also disclosed. L'invention concerne une forme polymorphe du maléate de bétrixaban et sur son procédé de préparation. L'invention concerne également une dispersion solide du polymorphe de maléate de bétrixaban avec des excipients pharmaceutiquement acceptables et leurs procédés de préparation. L'invention concerne également des formes polymorphes de base de bétrixaban et des procédés de préparation de celles-ci.