BIOPRODUCTION OF ACETALDEHYDE BY REORIENTATION OF THE FERMENTATION METABOLISM OF S. CEREVISIAE

The present invention relates to a genetically modified yeast strain, and to a method for the bioproduction of acetaldehyde using this strain. More particularly, the invention relates to a strain of S. cerevisiae which expresses an exogenous NADH oxidase and in which the gene ΑDH1 is inactivated. Cu...

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Hauptverfasser:	GOGNIES, Sabine, GUICHEBARD, Pierre, BELARBI, Abdelkader
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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creator	GOGNIES, Sabine GUICHEBARD, Pierre BELARBI, Abdelkader
description	The present invention relates to a genetically modified yeast strain, and to a method for the bioproduction of acetaldehyde using this strain. More particularly, the invention relates to a strain of S. cerevisiae which expresses an exogenous NADH oxidase and in which the gene ΑDH1 is inactivated. Cultured in a medium comprising approximately 5% sugars, in the presence of a bubbling process permitting continuous extraction of the acetaldehyde produced, said strain permits the ready production of acetaldehyde. La présente invention concerne une souche de levure génétiquement modifiée, ainsi qu'un procédé de bioproduction d'acétaldéhyde utilisant cette souche. Plus particulièrement, l'invention concerne une souche de S. cerevisiae exprimant une NADH oxydase exogène et dans laquelle le gène ΑDH1 est inactivé. Mise en culture dans un milieu comprenant environ 5% de sucres et en présence d'un bullage permettant l'extraction en continu de l'acétaldéhyde produit, cette souche permet une production aisée d'acétaldéhyde.
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CEREVISIAE</title><source>esp@cenet</source><creator>GOGNIES, Sabine ; GUICHEBARD, Pierre ; BELARBI, Abdelkader</creator><creatorcontrib>GOGNIES, Sabine ; GUICHEBARD, Pierre ; BELARBI, Abdelkader</creatorcontrib><description>The present invention relates to a genetically modified yeast strain, and to a method for the bioproduction of acetaldehyde using this strain. More particularly, the invention relates to a strain of S. cerevisiae which expresses an exogenous NADH oxidase and in which the gene ΑDH1 is inactivated. Cultured in a medium comprising approximately 5% sugars, in the presence of a bubbling process permitting continuous extraction of the acetaldehyde produced, said strain permits the ready production of acetaldehyde. La présente invention concerne une souche de levure génétiquement modifiée, ainsi qu'un procédé de bioproduction d'acétaldéhyde utilisant cette souche. Plus particulièrement, l'invention concerne une souche de S. cerevisiae exprimant une NADH oxydase exogène et dans laquelle le gène ΑDH1 est inactivé. Mise en culture dans un milieu comprenant environ 5% de sucres et en présence d'un bullage permettant l'extraction en continu de l'acétaldéhyde produit, cette souche permet une production aisée d'acétaldéhyde.</description><language>eng ; fre</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180329&DB=EPODOC&CC=WO&NR=2018055308A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180329&DB=EPODOC&CC=WO&NR=2018055308A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GOGNIES, Sabine</creatorcontrib><creatorcontrib>GUICHEBARD, Pierre</creatorcontrib><creatorcontrib>BELARBI, Abdelkader</creatorcontrib><title>BIOPRODUCTION OF ACETALDEHYDE BY REORIENTATION OF THE FERMENTATION METABOLISM OF S. 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CEREVISIAE</title><date>2018-03-29</date><risdate>2018</risdate><abstract>The present invention relates to a genetically modified yeast strain, and to a method for the bioproduction of acetaldehyde using this strain. More particularly, the invention relates to a strain of S. cerevisiae which expresses an exogenous NADH oxidase and in which the gene ΑDH1 is inactivated. Cultured in a medium comprising approximately 5% sugars, in the presence of a bubbling process permitting continuous extraction of the acetaldehyde produced, said strain permits the ready production of acetaldehyde. La présente invention concerne une souche de levure génétiquement modifiée, ainsi qu'un procédé de bioproduction d'acétaldéhyde utilisant cette souche. Plus particulièrement, l'invention concerne une souche de S. cerevisiae exprimant une NADH oxydase exogène et dans laquelle le gène ΑDH1 est inactivé. Mise en culture dans un milieu comprenant environ 5% de sucres et en présence d'un bullage permettant l'extraction en continu de l'acétaldéhyde produit, cette souche permet une production aisée d'acétaldéhyde.</abstract><oa>free_for_read</oa></addata></record>
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subjects	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
title	BIOPRODUCTION OF ACETALDEHYDE BY REORIENTATION OF THE FERMENTATION METABOLISM OF S. CEREVISIAE
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