APPARATUS AND METHOD FOR HANDHELD FREE-FORM BIOFABRICATION

Device and methods for free-form biofabrication, the device comprising a plurality of extrusion chambers that are hand-holdable and individually actuatable, an extrusion nozzle having a plurality of openings that are closely adjacent one another and respectively fluidly connected to the plurality of...

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Bibliographische Detailangaben
Hauptverfasser:	BEIRNE, Stephen Thomas, RICHARDS, Christopher John, YUE, Zhilian, TAYLOR, Adam Christopher, WALLACE, Gordon George, CHOONG, Peter, DI BELLA, Claudia, THOMPSON, Fletcher William
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DIAGNOSIS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE IDENTIFICATION MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS PROSTHESES SPIRITS SURGERY TREATMENT OR PROTECTION OF EYES OR EARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Device and methods for free-form biofabrication, the device comprising a plurality of extrusion chambers that are hand-holdable and individually actuatable, an extrusion nozzle having a plurality of openings that are closely adjacent one another and respectively fluidly connected to the plurality of extrusion chambers, wherein one of the extrusion chambers contains a bioink that comprises living cells which, in use, are controllably deliverable in situ with a structural biomaterial to form a biofabricated structure. L'invention concerne un dispositif et des procédés de biofabrication de forme libre, le dispositif comprenant une pluralité de chambres d'extrusion qui peuvent être tenues à la main et actionnables individuellement, une buse d'extrusion comprenant une pluralité d'ouvertures qui sont très proches les unes des autres et respectivement en liaison fluidique avec la pluralité de chambres d'extrusion, l'une des chambres d'extrusion contenant une bioencre qui comprend des cellules vivantes qui, lors de l'utilisation, peuvent être délivrées de manière contrôlée in situ avec un biomatériau structurel pour former une structure biofabriquée.