METHODS OF GENETICALLY ALTERING YEAST TO PRODUCE YEAST VARIANTS

A method of genetically altering a cell is provided including combining the cell including a target genomic sequence with a vector including an oligonucleotide sequence including a unique gene drive and nucleic acid sequences that target the target genomic sequence, wherein the unique gene drive is...

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Bibliographische Detailangaben
Hauptverfasser:	GUO, Xiaoge, CHAVEZ, Alejandro, KAAS, Christian Schroeder
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method of genetically altering a cell is provided including combining the cell including a target genomic sequence with a vector including an oligonucleotide sequence including a unique gene drive and nucleic acid sequences that target the target genomic sequence, wherein the unique gene drive is inserted into the target genomic sequence to produce a genetically altered cell. La présente invention concerne une méthode de modification génétique d'une cellule consistant à combiner la cellule comprenant une séquence génomique cible avec un vecteur comprenant une séquence oligonucléotidique comprenant un forçage génétique unique et des séquences d'acide nucléique qui ciblent la séquence génomique cible, le forçage génétique unique étant inséré dans la séquence génomique cible pour produire une cellule génétiquement modifiée.