CD3 BINDING ANTIBODIES

The present invention relates to novel human CD3 antigen-binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also relates to bispecific antibody molecules capable of activating immune effector cells and their use in diagnosis and/or treatment...

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Bibliographische Detailangaben
Hauptverfasser:	HARRIS, Katherine, TRINKLEIN, Nathan, ALDRED, Shelley Force, VANSCHOOTEN, Wim, PHAM, Duy
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to novel human CD3 antigen-binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also relates to bispecific antibody molecules capable of activating immune effector cells and their use in diagnosis and/or treatment of various diseases. La présente invention concerne de nouveaux polypeptides de liaison d'antigène CD3 humain, leurs préparation et leur utilisation dans le traitement et/ou le diagnostic de différentes maladies, et concerne en outre des molécules de type anticorps bispécifiques capables d'activer des cellules effectrices immunitaires et leur utilisation dans le diagnostic et/ou le traitement de diverses maladies.