COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES

COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES

Provided are novel peptides of Formula SEQ ID No. 1: J1CysX1X2X3X4X5X6,ProX7ThrCysJ2J3(J4)5(J5)1; (SEQ ID No. 1 ) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are which are effective inhibitors of light chains to uromodulin. L'invention concerne de n...

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Bibliographische Detailangaben
Hauptverfasser: LEGER, Roger, CARUSO, Marie-Elaine, ROSSERT, Jerome
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided are novel peptides of Formula SEQ ID No. 1: J1CysX1X2X3X4X5X6,ProX7ThrCysJ2J3(J4)5(J5)1; (SEQ ID No. 1 ) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are which are effective inhibitors of light chains to uromodulin. L'invention concerne de nouveaux peptides de formule (SEQ ID No. 1 : J1CysX1X2X3X4X5X6,ProX7ThrCysJ2J3(J4)5(J5)1; (SEQ ID No. 1) L'invention concerne également des sels pharmaceutiquement acceptables de ceux-ci, et des compositions pharmaceutiques de ceux-ci, qui sont des inhibiteurs efficaces de chaînes légères à l'uromoduline.