PROCESS FOR THE PREPARATION OF VENETOCLAX

The present disclosure provides novel synthetic process for the preparation of venetoclax. The disclosed processes involve the use of novel intermediates. Processes for the preparation of these intermediates are also disclosed as well as methods for the preparation of particularly useful salts there...

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Hauptverfasser: JOSHI, Rajesh, JAYACHANDRA, Suresh Babu, TRIPATHI, Anil Kumar, SANGVIKAR, Yogesh, POKHARKAR, Kiran, VADALI, Lakshmanarao, CHAUDHARI, Chandrakant, GOTTUMUKKALA, Nagaraju
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creator JOSHI, Rajesh
JAYACHANDRA, Suresh Babu
TRIPATHI, Anil Kumar
SANGVIKAR, Yogesh
POKHARKAR, Kiran
VADALI, Lakshmanarao
CHAUDHARI, Chandrakant
GOTTUMUKKALA, Nagaraju
description The present disclosure provides novel synthetic process for the preparation of venetoclax. The disclosed processes involve the use of novel intermediates. Processes for the preparation of these intermediates are also disclosed as well as methods for the preparation of particularly useful salts thereof. La présente invention concerne un nouveau procédé de synthèse pour la préparation de vénétoclax. Les procédés de l'invention impliquent l'utilisation de nouveaux intermédiaires. L'invention concerne également des procédés de préparation de ces intermédiaires ainsi que des procédés pour la préparation de sels particulièrement utiles de ceux-ci.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR THE PREPARATION OF VENETOCLAX
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