PROCESS FOR THE PREPARATION OF VENETOCLAX

The present disclosure provides novel synthetic process for the preparation of venetoclax. The disclosed processes involve the use of novel intermediates. Processes for the preparation of these intermediates are also disclosed as well as methods for the preparation of particularly useful salts there...

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Bibliographische Detailangaben
Hauptverfasser:	JOSHI, Rajesh, JAYACHANDRA, Suresh Babu, TRIPATHI, Anil Kumar, SANGVIKAR, Yogesh, POKHARKAR, Kiran, VADALI, Lakshmanarao, CHAUDHARI, Chandrakant, GOTTUMUKKALA, Nagaraju
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides novel synthetic process for the preparation of venetoclax. The disclosed processes involve the use of novel intermediates. Processes for the preparation of these intermediates are also disclosed as well as methods for the preparation of particularly useful salts thereof. La présente invention concerne un nouveau procédé de synthèse pour la préparation de vénétoclax. Les procédés de l'invention impliquent l'utilisation de nouveaux intermédiaires. L'invention concerne également des procédés de préparation de ces intermédiaires ainsi que des procédés pour la préparation de sels particulièrement utiles de ceux-ci.