SUBSTITUTED HYDANTOIN AND THIOHYDANTOIN DERIVATIVES AS ANDROGEN RECEPTOR ANTAGONISTS

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the antagonism of one or more androgen receptor types. Such compounds are represented by Formula (I), wherein R1, R2a, R,2b, Z, X and Y are defined herein and G is selected (g1) or (g2). L'invention...

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Bibliographische Detailangaben
1. Verfasser:	BIGNAN, Gilles C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compounds, compositions and methods for treating of disorders that are affected by the antagonism of one or more androgen receptor types. Such compounds are represented by Formula (I), wherein R1, R2a, R,2b, Z, X and Y are defined herein and G is selected (g1) or (g2). L'invention concerne des composés, des compositions et des méthodes de traitement de troubles qui sont affectés par l'antagonisme d'un ou plusieurs type de récepteur d'androgènes. De tels composés sont représentés par la formule (I), dans laquelle R1, R2a, R,2b, Z, X et Y sont définis ici et g est choisi parmi (g1) ou (g2).