NOVEL HYDRAZIDE CONTAINING COMPOUNDS AS BTK INHIBITORS

The present invention relates to novel hydrazide containing compounds as Bruton tyrosine kinase inhibitors, process of preparation thereof, and to the use of the compounds in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders involving mediation of Bruton tyros...

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Bibliographische Detailangaben
Hauptverfasser:	SAVANT, Pratit Viram, RATHOD, Rajendrasinh Jashvantsinh, BHATT, Tushar Bhupendrabhai, CHAUDHARI, Umesh Vishnu, KADIYALA, V.S.N. Murty, RAUT, Virendra Narendra, JOSHI, Kiritkumar Parmeshkumar, DESAI, Dipali Manubhai, CHITTURI, Trinadha Rao
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel hydrazide containing compounds as Bruton tyrosine kinase inhibitors, process of preparation thereof, and to the use of the compounds in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders involving mediation of Bruton tyrosine kinase in humans. La présente invention concerne de nouveaux composés contenant de l'hydrazide utilisés comme inhibiteurs de la tyrosine kinase de Bruton, leur procédé de préparation, et l'utilisation desdits composés dans la préparation de compositions pharmaceutiques pour le traitement thérapeutique de troubles impliquant une médiation de la tyrosine kinase de Bruton chez l'homme.