KRAS G12C INHIBITORS

The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor. La présente invention concerne des compo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	HINKLIN, Ronald, Jay, BURGESS, Laurence, E, SAVECHENKOV, Pavel, VIGERS, Guy, P.A, MARX, Matthew, Arnold, ZECCA, Henry, J, BLAKE, James, F, FELL, Jay, Bradford, LEE, Matthew, Randolf, MEJIA, Macedonio, J, HICKEN, Erik, James, GAUDINO, John, J, CHRISTENSEN, James, Gail, FISCHER, John, P, CHICARELLI, Mark, Joseph
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor. La présente invention concerne des composés qui inhibent l'activité de KRas G12C. En particulier, la présente invention concerne des composés qui inhibent de manière irréversible l'activité de KRas G12C, des compositions pharmaceutiques comprenant lesdits composés et des procédés d'utilisation de ceux-ci.