PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF

The present application relate to process for preparation of octahydropyrano [3, 2-b] pyran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts. La présente invention concerne un procédé...

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Hauptverfasser: GOVINDA PUR, Rajeshwar Reddy, HINDUPUR, Rama Mohan, NIKUMBH, Satish Pandurang, VALAVALA, Narayana Murthy, AKULA, Raghunadh, COBLEY, Christopher James, LLOYD, Michael Charles, KOTA BALAJI, Shiva Kumar, DAHANUKAR, Vilas Hareshwar, KOTTE, Rajashekar, DAVIDSON, Robert Wen Ming, JAMMULA, Subbarao
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present application relate to process for preparation of octahydropyrano [3, 2-b] pyran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts. La présente invention concerne un procédé de préparation de composé octahydropyrano [3, 2-b] pyrane de formule II, qui est utile en tant qu'intermédiaire pour la préparation d'analogues de l'halichondrine B tels que l'éribuline ou ses sels pharmaceutiquement acceptables.