MODIFIED PARTICLES OF CRYSTALLINE PALBOCICLIB FREE BASE AND PROCESS FOR THE PREPARATION THEREOF

The invention relates to modified particles of crystalline Palbociclib free base is having a specific surface area in the range from 7 to 15 m2jg. The invention further relates to Palbociclib free base form B is having a specific surface area in the range from 3 to 15 m /g and Palbociclib free base...

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Bibliographische Detailangaben
Hauptverfasser:	MANE, Narendra, Dattatraya, NEHATE, Sagar, Purushottam, SINGH, Girij, Pal, GODBOLE, Himanshu, Madhav
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to modified particles of crystalline Palbociclib free base is having a specific surface area in the range from 7 to 15 m2jg. The invention further relates to Palbociclib free base form B is having a specific surface area in the range from 3 to 15 m /g and Palbociclib free base form A is having a specific surface area in the range from 7 to 15 m 2jg, and its process for the preparation thereof. La présente invention concerne des particules modifiées de base libre de palbociclib cristallin ayant une surface spécifique située dans la plage de 7 à 15 m2jg. L'invention concerne en outre la forme base libre de palbociclib B ayant une surface spécifique située dans la plage de 3 à 15 m/g et la forme base libre de palbociclib A ayant une surface spécifique située dans la plage de 7 à 15 m2jg, et son procédé de préparation.