PROCESS FOR MAKING SUGAMMADEX
The invention relates to a novel process for making the pharmaceutical product Sugammadex. OVERVIEW OF THE PRIOR ART Sugammadex, i.e. 5-Cyclooctakis-(1→4)- [6-S-(2-carboxyethyl)-6-thio-alfa-D-glucopyranosyl] of formula (I), is a modified γ-cyclodextrin. Sugammadex is the first selective relaxant bin...
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| Zusammenfassung: | The invention relates to a novel process for making the pharmaceutical product Sugammadex. OVERVIEW OF THE PRIOR ART Sugammadex, i.e. 5-Cyclooctakis-(1→4)- [6-S-(2-carboxyethyl)-6-thio-alfa-D-glucopyranosyl] of formula (I), is a modified γ-cyclodextrin. Sugammadex is the first selective relaxant binding agent for reversal of neuromuscular blockade by the agent rocuronium or vecuronium in general anesthesia. It was approved in 2008
L'invention concerne un nouveau procédé de préparation du produit pharmaceutique sugammadex de formule (I)... |
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