REVERSIBLY-ACTIVATABLE ANTIBODY MIMETIC AND USE THEREOF

The present invention relates to the preparation of a reversibly-activatable antibody mimetic and the use thereof, and provides a fusion protein in which a first inactive fragment of an antibody mimetic is coupled with a stimulus-induced dimerization protein. La présente invention concerne la prépar...

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Bibliographische Detailangaben
Hauptverfasser: YU, Daseuli, PARK, Byung Ouk, HEO, Won Do, LEE, Yun Ju
Format: Patent
Sprache:eng ; fre ; kor
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Beschreibung
Zusammenfassung:The present invention relates to the preparation of a reversibly-activatable antibody mimetic and the use thereof, and provides a fusion protein in which a first inactive fragment of an antibody mimetic is coupled with a stimulus-induced dimerization protein. La présente invention concerne la préparation d'un mimétique d'anticorps pouvant être activé de manière réversible et son utilisation, et décrit une protéine de fusion dans laquelle un premier fragment inactif d'un mimétique d'anticorps est couplé à une protéine de dimérisation induite par un stimulus. 본 발명은 가역적으로 활성화되는 항체 유사체의 제조 및 그의 용도에 관한 것으로서, 항체 유사체의 비활성 제1단편에 지극-유도 이합체 형성 단백질이 연결된 융합단백질을 제공한다.