FLANGED GASTROINTESTINAL DEVICES AND METHODS OF USE THEREOF

The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange f...

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Hauptverfasser: MASTRI, Dominick, L, WILLIAMS, Nicholas, DICESARE, Paul, SCHORER, Scott, GREEN, Ronald, L, RADZIUNAS, Jeffrey, P
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Sprache:eng ; fre
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creator MASTRI, Dominick, L
WILLIAMS, Nicholas
DICESARE, Paul
SCHORER, Scott
GREEN, Ronald, L
RADZIUNAS, Jeffrey, P
description The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange for attachment to a luminal wall proximal to the pyloric orifice. The invention also provides methods of use associated with such gastrointestinal devices, including methods for delivery, removal, and treatment of metabolic disorders, such as type 2 diabetes, non-alcoholic steatohepatitis, non-alcoholic fatty liver disease, obesity, and related comorbidities thereof by implanting gastrointestinal devices. La présente invention concerne des dispositifs gastro-intestinaux pour limiter le transfert et le contact de matière sur les parois intracavitaires le long d'un segment du tractus gastro-intestinal (par exemple, au niveau du duodénum et/ou jéjunum supérieur). Des dispositifs de l'invention comprennent un manchon gastro-intestinal, un ancrage et un rebord pour la fixation à une paroi intracavitaire proximale à l'orifice pylorique. L'invention concerne également des procédés d'utilisation associés auxdits dispositifs gastro-intestinaux, comprenant des procédés de pose, de retrait et de traitement de troubles métaboliques, tels que le diabète de type 2, la stéatohépatite non-alcoolique, la stéatose hépatique non-alcoolique, l'obésité et leurs comorbidités associées par implantation de dispositifs gastro-intestinaux.
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subjects BANDAGES, DRESSINGS OR ABSORBENT PADS
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DIAGNOSIS
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROSTHESES
SURGERY
TREATMENT OR PROTECTION OF EYES OR EARS
title FLANGED GASTROINTESTINAL DEVICES AND METHODS OF USE THEREOF
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