FLANGED GASTROINTESTINAL DEVICES AND METHODS OF USE THEREOF

The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange f...

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Bibliographische Detailangaben
Hauptverfasser:	MASTRI, Dominick, L, WILLIAMS, Nicholas, DICESARE, Paul, SCHORER, Scott, GREEN, Ronald, L, RADZIUNAS, Jeffrey, P
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DIAGNOSIS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE IDENTIFICATION MEDICAL OR VETERINARY SCIENCE ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES SURGERY TREATMENT OR PROTECTION OF EYES OR EARS
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Beschreibung
Zusammenfassung:	The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange for attachment to a luminal wall proximal to the pyloric orifice. The invention also provides methods of use associated with such gastrointestinal devices, including methods for delivery, removal, and treatment of metabolic disorders, such as type 2 diabetes, non-alcoholic steatohepatitis, non-alcoholic fatty liver disease, obesity, and related comorbidities thereof by implanting gastrointestinal devices. La présente invention concerne des dispositifs gastro-intestinaux pour limiter le transfert et le contact de matière sur les parois intracavitaires le long d'un segment du tractus gastro-intestinal (par exemple, au niveau du duodénum et/ou jéjunum supérieur). Des dispositifs de l'invention comprennent un manchon gastro-intestinal, un ancrage et un rebord pour la fixation à une paroi intracavitaire proximale à l'orifice pylorique. L'invention concerne également des procédés d'utilisation associés auxdits dispositifs gastro-intestinaux, comprenant des procédés de pose, de retrait et de traitement de troubles métaboliques, tels que le diabète de type 2, la stéatohépatite non-alcoolique, la stéatose hépatique non-alcoolique, l'obésité et leurs comorbidités associées par implantation de dispositifs gastro-intestinaux.