CRYSTALLINE AND AMORPHOUS FORMS OF CARFILZOMIB

The present disclosure provides crystalline carfilzomib form M1 and a process for the preparation thereof. Further disclosed are processes for the preparation of amorphous carfilzomib using crystalline form M1 as a starting material.The present disclosure also relates to an improved process for the...

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Bibliographische Detailangaben
Hauptverfasser:	KOKANE, Dattatrey, SANGVIKAR, Yogesh, SHUKLA, Vinay Kumar, GHARAT, Sushant, GORE, Vinayak G
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present disclosure provides crystalline carfilzomib form M1 and a process for the preparation thereof. Further disclosed are processes for the preparation of amorphous carfilzomib using crystalline form M1 as a starting material.The present disclosure also relates to an improved process for the preparation of carfilzomib. La présente invention concerne une forme cristalline de carfilzomib M1 et un procédé de préparation associé. L'invention concerne également des procédés de préparation de carfilzomib amorphe utilisant la forme cristalline M1 comme matière de départ. La présente invention concerne également un procédé amélioré de préparation de carfilzomib.