POTENT PHTHALATE INHIBITORS OF ASPARTATE N-ACETYLTRANSFERASE AND SELECTIVE ASPARTATE PATHWAY INHIBITORS

Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same. La présente invention concerne des dérivés phtala...

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Hauptverfasser: THANGAVELU, Bharani, MUTTHAMSETTY, Vinay, WANG, Qinzhe, VIOLA, Ronald, E, BHANSALI, Pravin
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Phthalate derivatives that are aspartate-P-semialdehyde dehydrogenase (ASADH) inhibitor compounds, aspartate N-acetyltransferase (ANAT) inhibitor compounds, or both, are described, as well as methods of making the same, and methods of using the same. La présente invention concerne des dérivés phtalate qui sont des composés d'inhibiteur de l'aspartate-P-semialdéhyde déshydrogénase (ASADH), des composés d'inhibiteur de l'aspartate N-acétyltransférase (ANAT) ou bien les deux, ainsi que des procédés de fabrication de ceux-ci, et des procédés d'utilisation correspondants.