SOLID STATE FORMS OF N-[2-[(1 S)-1 -(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYL SULFONYL)ETHYL]-2,3-DIHYDRO-1,3-DIOXO-L H-ISOINDOL-4-YL]ACETAMIDE AND PROCESS FOR PREPARATION THEREOF
The present invention, relates to solid state forms of N-[2-[(l S)-l-(3-ethoxy-4- methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acetamide represented by the following structural formula- 1 and process for their preparation. The present invention also relates to an im...
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| creator | PRADEEP, Rebelli ESWARAIAH, Sajja THIRUMALAI RAJAN, Srinivasan VENKAT REDDY, Ghojala |
| description | The present invention, relates to solid state forms of N-[2-[(l S)-l-(3-ethoxy-4- methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acetamide represented by the following structural formula- 1 and process for their preparation. The present invention also relates to an improved process for the preparation of N-[2- [(l S)-l-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acetamide compound of formula- 1 and intermediates thereof.
La présente invention concerne des formes à l'état solide de N-[2-[(l S)-l-(3-éthoxy-4- méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acétamide représenté par la formule structurelle suivante -1 et le procédé de préparation associé. La présente invention concerne également un procédé amélioré pour la préparation du composé N-[2- [(l S)-l-(3-éthoxy-4-méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acétamide de formule -1 et des intermédiaires de celui-ci. |
| format | Patent |
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La présente invention concerne des formes à l'état solide de N-[2-[(l S)-l-(3-éthoxy-4- méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acétamide représenté par la formule structurelle suivante -1 et le procédé de préparation associé. La présente invention concerne également un procédé amélioré pour la préparation du composé N-[2- [(l S)-l-(3-éthoxy-4-méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acétamide de formule -1 et des intermédiaires de celui-ci.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170406&DB=EPODOC&CC=WO&NR=2017033206A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170406&DB=EPODOC&CC=WO&NR=2017033206A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PRADEEP, Rebelli</creatorcontrib><creatorcontrib>ESWARAIAH, Sajja</creatorcontrib><creatorcontrib>THIRUMALAI RAJAN, Srinivasan</creatorcontrib><creatorcontrib>VENKAT REDDY, Ghojala</creatorcontrib><title>SOLID STATE FORMS OF N-[2-[(1 S)-1 -(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYL SULFONYL)ETHYL]-2,3-DIHYDRO-1,3-DIOXO-L H-ISOINDOL-4-YL]ACETAMIDE AND PROCESS FOR PREPARATION THEREOF</title><description>The present invention, relates to solid state forms of N-[2-[(l S)-l-(3-ethoxy-4- methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acetamide represented by the following structural formula- 1 and process for their preparation. The present invention also relates to an improved process for the preparation of N-[2- [(l S)-l-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acetamide compound of formula- 1 and intermediates thereof.
La présente invention concerne des formes à l'état solide de N-[2-[(l S)-l-(3-éthoxy-4- méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acétamide représenté par la formule structurelle suivante -1 et le procédé de préparation associé. La présente invention concerne également un procédé amélioré pour la préparation du composé N-[2- [(l S)-l-(3-éthoxy-4-méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acétamide de formule -1 et des intermédiaires de celui-ci.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjsFqwzAQRH3pITT5h4VeHMiCLZX2LKwVEshaI6k0JpQQinoqbSD5rnxj7LQfkNO8GYZhFtUlsXcaUlaZwHDsE7CBgDuBu7qFtMYWsJZI2fJ2xGfs_2iwFEa_RoH1nIwe0ps3PGc3-4FiI1E7O-rI2N6Yt4weLLrELmj209pUVB1l1TtNoIKGIXJHKc1XJqZBRZUdB8iWIrFZVg9fh-9TWf3rY_VkKHcWy_F3X07Hw2f5Kef9O4umfW2kFM2LkvK-1hVBiUhA</recordid><startdate>20170406</startdate><enddate>20170406</enddate><creator>PRADEEP, Rebelli</creator><creator>ESWARAIAH, Sajja</creator><creator>THIRUMALAI RAJAN, Srinivasan</creator><creator>VENKAT REDDY, Ghojala</creator><scope>EVB</scope></search><sort><creationdate>20170406</creationdate><title>SOLID STATE FORMS OF N-[2-[(1 S)-1 -(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYL SULFONYL)ETHYL]-2,3-DIHYDRO-1,3-DIOXO-L H-ISOINDOL-4-YL]ACETAMIDE AND PROCESS FOR PREPARATION THEREOF</title><author>PRADEEP, Rebelli ; ESWARAIAH, Sajja ; THIRUMALAI RAJAN, Srinivasan ; VENKAT REDDY, Ghojala</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2017033206A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>PRADEEP, Rebelli</creatorcontrib><creatorcontrib>ESWARAIAH, Sajja</creatorcontrib><creatorcontrib>THIRUMALAI RAJAN, Srinivasan</creatorcontrib><creatorcontrib>VENKAT REDDY, Ghojala</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PRADEEP, Rebelli</au><au>ESWARAIAH, Sajja</au><au>THIRUMALAI RAJAN, Srinivasan</au><au>VENKAT REDDY, Ghojala</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SOLID STATE FORMS OF N-[2-[(1 S)-1 -(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYL SULFONYL)ETHYL]-2,3-DIHYDRO-1,3-DIOXO-L H-ISOINDOL-4-YL]ACETAMIDE AND PROCESS FOR PREPARATION THEREOF</title><date>2017-04-06</date><risdate>2017</risdate><abstract>The present invention, relates to solid state forms of N-[2-[(l S)-l-(3-ethoxy-4- methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acetamide represented by the following structural formula- 1 and process for their preparation. The present invention also relates to an improved process for the preparation of N-[2- [(l S)-l-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acetamide compound of formula- 1 and intermediates thereof.
La présente invention concerne des formes à l'état solide de N-[2-[(l S)-l-(3-éthoxy-4- méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-lH-isoindol-4-yl]acétamide représenté par la formule structurelle suivante -1 et le procédé de préparation associé. La présente invention concerne également un procédé amélioré pour la préparation du composé N-[2- [(l S)-l-(3-éthoxy-4-méthoxyphényl)-2-(méthylsulfonyl)éthyl]-2,3-dihydro-l,3-dioxo-l H- isoindol-4-yl]acétamide de formule -1 et des intermédiaires de celui-ci.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | SOLID STATE FORMS OF N-[2-[(1 S)-1 -(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYL SULFONYL)ETHYL]-2,3-DIHYDRO-1,3-DIOXO-L H-ISOINDOL-4-YL]ACETAMIDE AND PROCESS FOR PREPARATION THEREOF |
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