LIQUID PHARMACEUTICAL COMPOSITIONS COMPRISING SGLT-2 INHIBITORS

The invention relates to novel liquid pharmaceutical compositions comprising at least one SGLT-2 inhibitor and one or more polar organic solvents, wherein the at least one SGLT-2 inhibitor comprises 1-cyano-2-(4- cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene according to formula (I): as well...

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Hauptverfasser: PRIDDY, Timothy, Shane, STETTLER, Heike, WEILER, Claudius, HAASE, Marbod, DUCH, Thomas, Adam
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to novel liquid pharmaceutical compositions comprising at least one SGLT-2 inhibitor and one or more polar organic solvents, wherein the at least one SGLT-2 inhibitor comprises 1-cyano-2-(4- cyclopropyl-benzyl)-4-(β-D-glucopyranos-1-yl)-benzene according to formula (I): as well as corresponding processes of manufacturing such liquid pharmaceutical compositions and their medical uses. L'invention concerne de nouvelles compositions pharmaceutiques liquides comprenant au moins un inhibiteur de SGLT-2 et un ou plusieurs solvants organiques polaires, le ou les inhibiteur(s) de SGLT-2 comprenant 1-cyano-2-(4-cyclopropyl-benzyle)-4-(bêta-D-glucopyranos-1-yl)-benzène selon la formule (I) : ainsi que des procédés correspondants de fabrication de telles compositions pharmaceutiques liquides et leurs utilisations médicales.