A CARBON DIOXIDE ADDUCT OF PALBOCICLIB

The present invention provides a carbon dioxide adduct of palbociclib designated as crystalline Form VA. It also relates to the preparation of a carbon dioxide adduct of palbociclib, its pharmaceutical composition, and its use for the treatment of cyclin- dependent kinase (cdk) associated diseases....

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Bibliographische Detailangaben
Hauptverfasser: TYAGI, Vipin, GANGULY, Somenath, PANDA, Tapas, MOHAMMAD, Kallimulla, RAI, Bishwa, Prakash
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides a carbon dioxide adduct of palbociclib designated as crystalline Form VA. It also relates to the preparation of a carbon dioxide adduct of palbociclib, its pharmaceutical composition, and its use for the treatment of cyclin- dependent kinase (cdk) associated diseases. La présente invention concerne un produit d'addition au dioxyde de carbone de palbociclib appelé Forme cristalline VA. L'invention concerne également la préparation d'un produit d'addition au dioxyde de carbone de palbociclib, sa composition pharmaceutique, et son utilisation pour le traitement de maladies associées aux kinases dépendantes des cyclines (cdk).