NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS

NOVEL BETULINIC SUBSTITUTED AMIDE DERIVATIVES AS HIV INHIBITORS

The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. The invention novel betulinic substituted amide derivatives, re...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: NEELA, Sudhakar, LANKA, Vl Subrahmanyam, BANDI, Parthasaradhi Reddy, KURA, Rathnakar Reddy, ADULLA, Panduranga Reddy, MUKKERA, Venkati, GAZULA LEVI, David Krupadanam
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
STEROIDS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to novel betulinic substituted amide compounds of formula (I); and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, Z3 and are Formula (II) as defined herein. The invention novel betulinic substituted amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases. L'invention concerne de nouveaux composés amide substitués de formule (I) et leurs sels pharmaceutiquement acceptables. Dans la formule (I), R1, R2, R3, R4, R5, R6, R7, R8, X, Y, Z1, Z2, et Z3 sont tels que définis dans la description. La présente invention concerne de nouveaux dérivés d'amide substitués bétuliniques, des composés apparentés, et des compositions pharmaceutiques utiles pour le traitement thérapeutique de maladies virales et en particulier de maladies induites par le VIH.