METHODS FOR TREATING AND PREVENTING POLYCYSTIC KIDNEY DISEASES (PKD) USING AMP-ACTIVATED PROTEIN KINASE (AMPK) MODULATORS AND ACTIVATORS

Methods for treating polycystic kidney disease (PKD) in a subject comprising administering a 5'-adenosine monophosphate (AMP)-activated protein kinase (AMPK) modulator or activator. Also kits comprising AMPK modulator or activators and instruction for their use in treating PKD. L'invention...

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Bibliographische Detailangaben
Hauptverfasser:	LEGER, Roger, DUBE, Gilles, ROSSERT, Jerome
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Methods for treating polycystic kidney disease (PKD) in a subject comprising administering a 5'-adenosine monophosphate (AMP)-activated protein kinase (AMPK) modulator or activator. Also kits comprising AMPK modulator or activators and instruction for their use in treating PKD. L'invention concerne des méthodes de traitement de la polykystose rénale (PKD) chez un sujet, comprenant l'administration d'un modulateur ou d'un activateur de 5'-adénosine monophosphate protéine kinase activée par l'AMP (AMPK). L'invention concerne également des kits comprenant un modulateur ou des activateurs de l'AMPK et les instructions pour leur utilisation pour le traitement de la PKD.