SACUBITRIL CALCIUM SALTS

The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MUELLER, Sibylle, HOOK, David, WAYKOLE, Liladhar Murlidhar, WIETFELD, Bernhard, MEIER, Ulrich, HU, Bin, KLEINBECK, Florian Karl, MUTZ, Jean-Paul, SUTTON, Paul Allen, SCHLOMACH, Jan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases. L'invention concerne des formes polymorphes du sel de calcium de l'ester éthylique d'acide N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phénylphénylmethyl)-4-amino-(2R)-méthyl butanoïque. Le sel de calcium de l'ester éthylique d'acide N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phénylphénylméthyl)-4-amino-(2R)-méthyl butanoïque est utile dans le traitement de divers états et troubles réagissant à l'inhibition d'endopeptidases neutres.