SKIN WHITENING COMPOSITION, AND METHOD FOR SCREENING FOR MATERIALS HAVING SKIN WHITENING EFFECT
Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apopto...
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Sprache: | eng ; fre ; kor |
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Zusammenfassung: | Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apoptosis of melanocytes by inhibiting the amount of secretion of exosomes to be secreted from melanocytes, and consequently inhibits the generation of melanin through the apoptosis of melanocytes, thereby exhibiting a skin whitening effect.
La présente invention concerne : une composition de blanchiment de peau ayant un effet de blanchiment de peau par régulation de la sécrétion d'exosomes à sécréter à partir de mélanocytes; et un procédé de criblage de matières ayant un effet de blanchiment de peau. La composition de blanchiment de peau peut favoriser l'apoptose de mélanocytes par inhibition de la quantité de sécrétion d'exosomes à sécréter à partir de mélanocytes et, par conséquent, inhibe la génération de mélanine par l'intermédiaire de l'apoptose de mélanocytes, en présentant ainsi un effet de blanchiment de peau.
본 명세서에는 멜라닌형성세포에서 분비되는 엑소좀의 분비 제어를 통해 피부 미백에 효능이 있는 피부 미백용 조성물 및 피부 미백 효능 물질을 스크리닝하는 방법이 개시된다. 상기 피부 미백용 조성물은 멜라닌형성세포에서 분비되는 엑소좀의 분비량을 억제시킴으로써 멜라닌형성세포의 세포사멸을 증가시킬 수 있고, 이러한 멜라닌형성세포의 세포사멸로 인해 결과적으로 멜라닌 생성을 저해하여 미백 효능이 발휘되는 효과가 있다. |
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