METHODS FOR TREATING TUMORS IN SITU INCLUDING INTRATUMOR INJECTION OF CYTOTOXIC PARTICLES AND IMMUNE CHECKPOINT BLOCKADE THERAPY

Disclosed are compositions, kits, and methods for treating cancer in a subject in need thereof. The compositions, kits, and methods may be used to treat a tumor in a subject in situ. The compositions, kits, and methods comprise or utilize cytotoxic particles, immune checkpoint inhibitors, and/or T-c...

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Bibliographische Detailangaben
Hauptverfasser:	SALEM, Aliasger, K, JOSHI, Vijaya, B, MAKKOUK, Amani, WEINER, George
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compositions, kits, and methods for treating cancer in a subject in need thereof. The compositions, kits, and methods may be used to treat a tumor in a subject in situ. The compositions, kits, and methods comprise or utilize cytotoxic particles, immune checkpoint inhibitors, and/or T-cell stimulatory agents. L'invention concerne des compositions, kits et méthodes pour traiter le cancer chez un sujet le nécessitant. Les compositions, kits, et méthodes peuvent être utilisés pour traiter une tumeur chez un sujet in situ. Les compositions, kits, et méthodes comprennent ou utilisent des particules cytotoxiques, des inhibiteurs de point de contrôle immunitaire, et/ou des agents stimulant les lymphocytes T.