BROMODOMAIN-INHIBITING COMPOUNDS AND METHODS TO PREVENT OR TREAT A CANCER

Provided is a novel compound inhibiting the bromodomain and extra terminal domain (BET) proteins, and a pharmaceutical composition comprising the same which can be useful for prevention or treatment of a precancerous transformation or a cancer. L'invention concerne un nouveau composé inhibant d...

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Bibliographische Detailangaben
Hauptverfasser:	OH, Su-Sung, CHOI, Minjeong
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided is a novel compound inhibiting the bromodomain and extra terminal domain (BET) proteins, and a pharmaceutical composition comprising the same which can be useful for prevention or treatment of a precancerous transformation or a cancer. L'invention concerne un nouveau composé inhibant des protéines à bromodomaine et domaine extra-terminal (BET), ainsi qu'une composition pharmaceutique comprenant ledit composé qui peut être utile pour prévenir ou traiter une transformation précancéreuse ou un cancer.