NOVEL PROCESS FOR THE PREPARATION OF PERAMPANEL AND ITS INTERMEDIATES THEREOF

The present invention provides novel process for preparation of 3-(2-cyanophenyl)-5-(2- pyridyl)-1-phenyl-1,2-dihydropyridin-2-one, commonly known as perampanel having the formula I. The present invention also provides novel intermediate compound of formula VI and process for the preparation of inte...

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Hauptverfasser: CHAUHAN, Nitesh Dolatram, KAPKOTI, Gobind Singh, LOURDUSAMY, Mettilda, RADU, Ioan Iosif, PATEL, Vishal Keshavlal, DHOLARIYA, Bipinkumar Hashmukhbhai, PANDYA, Ashesh Kamalnayan
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creator CHAUHAN, Nitesh Dolatram
KAPKOTI, Gobind Singh
LOURDUSAMY, Mettilda
RADU, Ioan Iosif
PATEL, Vishal Keshavlal
DHOLARIYA, Bipinkumar Hashmukhbhai
PANDYA, Ashesh Kamalnayan
description The present invention provides novel process for preparation of 3-(2-cyanophenyl)-5-(2- pyridyl)-1-phenyl-1,2-dihydropyridin-2-one, commonly known as perampanel having the formula I. The present invention also provides novel intermediate compound of formula VI and process for the preparation of intermediate compound of formula VI. The present invention also provides purification of perampanel. La présente invention concerne un nouveau procédé de préparation de 3-(2-cyanopshényl)-5-(2-pyridyl)-1-phényl -1,2-dihydropyridin-2-one, communément appelé perampanel ayant la formule I. La présente invention concerne également de nouveaux composés intermédiaires de la formule VI et un procédé de préparation de composés intermédiaires de la formule VI. La présente invention concerne également la purification de perampanel.
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The present invention also provides novel intermediate compound of formula VI and process for the preparation of intermediate compound of formula VI. The present invention also provides purification of perampanel. La présente invention concerne un nouveau procédé de préparation de 3-(2-cyanopshényl)-5-(2-pyridyl)-1-phényl -1,2-dihydropyridin-2-one, communément appelé perampanel ayant la formule I. La présente invention concerne également de nouveaux composés intermédiaires de la formule VI et un procédé de préparation de composés intermédiaires de la formule VI. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title NOVEL PROCESS FOR THE PREPARATION OF PERAMPANEL AND ITS INTERMEDIATES THEREOF
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