TSLP BINDING PROTEINS

TSLP BINDING PROTEINS

The present disclosure relates to TSLP binding proteins, such as anti-TSLP single variable domains, polynucleotides encoding such TSLP binding proteins, pharmaceutical compositions and kits comprising said TSLP binding proteins and methods of manufacture. The present invention also concerns the use...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DELLA CRISTINA, Pietro, BARTHOLOMEW, Michelle Anne, DIMECH, Caroline, AHMED, Farheen, MORLEY, Peter, SHAH, Rachana Shailesh, TILLING, Paula
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to TSLP binding proteins, such as anti-TSLP single variable domains, polynucleotides encoding such TSLP binding proteins, pharmaceutical compositions and kits comprising said TSLP binding proteins and methods of manufacture. The present invention also concerns the use of such TSLP binding proteins in the treatment of diseases associated TSLP signalling, such as asthma. La présente invention concerne des protéines de liaison à la TSLP, telles que des domaines variables uniques anti-TSLP, des polynucléotides codant ces protéines de liaison à la TSLP, des compositions pharmaceutiques et des kits comprenant lesdites protéines de liaison à la TSLP, et leur procédés de fabrication. La présente invention concerne également l'utilisation de telles protéines de liaison à la TSLP dans le traitement de maladies associées à la signalisation de la TSLP, telles que l'asthme.