CRYSTALLINE FORMS OF (R)-(2-(4-CHLOROPHENYL)QUINOLIN-4-YL) [(2S)-PIPERIDIN-2-YL]METHANOL

CRYSTALLINE FORMS OF (R)-(2-(4-CHLOROPHENYL)QUINOLIN-4-YL) [(2S)-PIPERIDIN-2-YL]METHANOL

The present invention relates to novel crystalline forms of Vacquinol-1, in particular novel crystalline forms of (R)-(2-(4-chlorophenyl)quinolin-4-yl)[(2S)- piperidin-2-yl]methanol and to methods for their preparation. The invention is 5 also directed to pharmaceutical compositions containing at le...

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Bibliographische Detailangaben
Hauptverfasser: LARSSON, Ulf, KINDSTEDT BOHLIN, Ann-Sofie, BOHLIN, Martin, ÅSLUND, Bengt, NORELAND, David, HAMMARSTRÖM, Lars, SVENSSON, Per H, YMÉN, Bengt
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to novel crystalline forms of Vacquinol-1, in particular novel crystalline forms of (R)-(2-(4-chlorophenyl)quinolin-4-yl)[(2S)- piperidin-2-yl]methanol and to methods for their preparation. The invention is 5 also directed to pharmaceutical compositions containing at least one such crystalline form, therapeutic or profylactic use of such crystalline forms and compositions and methods of preparing such crystalline forms. La présente invention concerne de nouvelles formes cristallines de Vacquinol-1, en particulier de nouvelles formes cristallines de (R)-(2-(4-chlorophényl)quinolin-4-yl)[(2S)-pipéridin-2-yl]méthanol et des procédés pour leur préparation. L'invention concerne également des compositions pharmaceutiques contenant au moins une telle forme cristalline, une utilisation thérapeutique ou prophylactique de ces formes cristallines et des compositions et des procédés de préparation de ces formes cristallines.