DEVICE, PLATFORM, AND ASSAY FOR ASSESSING CELLS

This invention provides devices capable of assessing the migration response in the presence of a stable encapsulated gradient of a factor or factor combination, and quantifying the adherence response inside micro-channels in the presence of different factors. This invention also provides a piatform...

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1. Verfasser: COX, Juan, Pablo, Acevedo
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description This invention provides devices capable of assessing the migration response in the presence of a stable encapsulated gradient of a factor or factor combination, and quantifying the adherence response inside micro-channels in the presence of different factors. This invention also provides a piatform for obtaining information relating to migration score or the quantification of adhered cells through use of the devices of the present invention, and it allows this information to be used to assess therapeutic potential Additionally, the invention provides a method to quantify the cells migration response and the cell adherence response. L'invention concerne des dispositifs capables d'évaluer la réponse de migration en présence d'un gradient stable encapsulé d'un facteur ou d'une combinaison de facteurs, et de quantifier la réponse d'adhérence dans les micro-canaux en présence de différents facteurs. L'invention concerne également une plateforme permettant d'obtenir des informations relatives au score de migration ou à la quantification des cellules adhérentes au moyen des dispositifs de l'invention, et permet d'exploiter ces informations afin d'évaluer un potentiel thérapeutique. De plus, l'invention concerne un procédé permettant de quantifier la réponse de migration des cellules ainsi que la réponse d'adhérence des cellules.
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subjects BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
TRANSPORTING
VINEGAR
WINE
title DEVICE, PLATFORM, AND ASSAY FOR ASSESSING CELLS
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