DEVICE, PLATFORM, AND ASSAY FOR ASSESSING CELLS

This invention provides devices capable of assessing the migration response in the presence of a stable encapsulated gradient of a factor or factor combination, and quantifying the adherence response inside micro-channels in the presence of different factors. This invention also provides a piatform...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	COX, Juan, Pablo, Acevedo
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	This invention provides devices capable of assessing the migration response in the presence of a stable encapsulated gradient of a factor or factor combination, and quantifying the adherence response inside micro-channels in the presence of different factors. This invention also provides a piatform for obtaining information relating to migration score or the quantification of adhered cells through use of the devices of the present invention, and it allows this information to be used to assess therapeutic potential Additionally, the invention provides a method to quantify the cells migration response and the cell adherence response. L'invention concerne des dispositifs capables d'évaluer la réponse de migration en présence d'un gradient stable encapsulé d'un facteur ou d'une combinaison de facteurs, et de quantifier la réponse d'adhérence dans les micro-canaux en présence de différents facteurs. L'invention concerne également une plateforme permettant d'obtenir des informations relatives au score de migration ou à la quantification des cellules adhérentes au moyen des dispositifs de l'invention, et permet d'exploiter ces informations afin d'évaluer un potentiel thérapeutique. De plus, l'invention concerne un procédé permettant de quantifier la réponse de migration des cellules ainsi que la réponse d'adhérence des cellules.