PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION
Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involve...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | ARDECKY, ROBERT, JOHN HASSIG, CHRISTIAN, A PINKERTON, ANTHONY, B PASS, IAN JACKSON, MICHAEL, R |
| description | Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis.
Cette invention concerne des composés de et des compositions pharmaceutiques les contenant. Les composés et compositions de l'invention sont utiles comme modulateurs de translocation du récepteurs des glucocorticoïdes (GR). En outre, les composés et compositions de l'invention sont utiles pour le traitement de maladies impliquant un dysfonctionnement de l'axe hypothalamo-pituito-surrénalien (HPS). |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2016123392A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2016123392A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2016123392A23</originalsourceid><addsrcrecordid>eNrjZPAKiAxyjPL38QfSnr6eLp5-rsEKjsEKnn4enk6eIf5BwQr-bgruPqHO_s7-QSGezv6eLgpBrs6uAUA5hZAgR79gH39nxxBPfz8eBta0xJziVF4ozc2g7OYa4uyhm1qQH59aXJCYnJqXWhIf7m9kYGhmaGRsbGnkaGRMnCoAiuEvLQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION</title><source>esp@cenet</source><creator>ARDECKY, ROBERT, JOHN ; HASSIG, CHRISTIAN, A ; PINKERTON, ANTHONY, B ; PASS, IAN ; JACKSON, MICHAEL, R</creator><creatorcontrib>ARDECKY, ROBERT, JOHN ; HASSIG, CHRISTIAN, A ; PINKERTON, ANTHONY, B ; PASS, IAN ; JACKSON, MICHAEL, R</creatorcontrib><description>Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis.
Cette invention concerne des composés de et des compositions pharmaceutiques les contenant. Les composés et compositions de l'invention sont utiles comme modulateurs de translocation du récepteurs des glucocorticoïdes (GR). En outre, les composés et compositions de l'invention sont utiles pour le traitement de maladies impliquant un dysfonctionnement de l'axe hypothalamo-pituito-surrénalien (HPS).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160804&DB=EPODOC&CC=WO&NR=2016123392A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160804&DB=EPODOC&CC=WO&NR=2016123392A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ARDECKY, ROBERT, JOHN</creatorcontrib><creatorcontrib>HASSIG, CHRISTIAN, A</creatorcontrib><creatorcontrib>PINKERTON, ANTHONY, B</creatorcontrib><creatorcontrib>PASS, IAN</creatorcontrib><creatorcontrib>JACKSON, MICHAEL, R</creatorcontrib><title>PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION</title><description>Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis.
Cette invention concerne des composés de et des compositions pharmaceutiques les contenant. Les composés et compositions de l'invention sont utiles comme modulateurs de translocation du récepteurs des glucocorticoïdes (GR). En outre, les composés et compositions de l'invention sont utiles pour le traitement de maladies impliquant un dysfonctionnement de l'axe hypothalamo-pituito-surrénalien (HPS).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAKiAxyjPL38QfSnr6eLp5-rsEKjsEKnn4enk6eIf5BwQr-bgruPqHO_s7-QSGezv6eLgpBrs6uAUA5hZAgR79gH39nxxBPfz8eBta0xJziVF4ozc2g7OYa4uyhm1qQH59aXJCYnJqXWhIf7m9kYGhmaGRsbGnkaGRMnCoAiuEvLQ</recordid><startdate>20160804</startdate><enddate>20160804</enddate><creator>ARDECKY, ROBERT, JOHN</creator><creator>HASSIG, CHRISTIAN, A</creator><creator>PINKERTON, ANTHONY, B</creator><creator>PASS, IAN</creator><creator>JACKSON, MICHAEL, R</creator><scope>EVB</scope></search><sort><creationdate>20160804</creationdate><title>PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION</title><author>ARDECKY, ROBERT, JOHN ; HASSIG, CHRISTIAN, A ; PINKERTON, ANTHONY, B ; PASS, IAN ; JACKSON, MICHAEL, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2016123392A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ARDECKY, ROBERT, JOHN</creatorcontrib><creatorcontrib>HASSIG, CHRISTIAN, A</creatorcontrib><creatorcontrib>PINKERTON, ANTHONY, B</creatorcontrib><creatorcontrib>PASS, IAN</creatorcontrib><creatorcontrib>JACKSON, MICHAEL, R</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ARDECKY, ROBERT, JOHN</au><au>HASSIG, CHRISTIAN, A</au><au>PINKERTON, ANTHONY, B</au><au>PASS, IAN</au><au>JACKSON, MICHAEL, R</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION</title><date>2016-08-04</date><risdate>2016</risdate><abstract>Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis.
Cette invention concerne des composés de et des compositions pharmaceutiques les contenant. Les composés et compositions de l'invention sont utiles comme modulateurs de translocation du récepteurs des glucocorticoïdes (GR). En outre, les composés et compositions de l'invention sont utiles pour le traitement de maladies impliquant un dysfonctionnement de l'axe hypothalamo-pituito-surrénalien (HPS).</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2016123392A2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T15%3A27%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ARDECKY,%20ROBERT,%20JOHN&rft.date=2016-08-04&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2016123392A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |