PYRAZOLOPYRIMIDINES AS INHIBITORS OF GLUCOCORTICOID RECEPTOR TRANSLOCATION

Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involve...

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Bibliographische Detailangaben
Hauptverfasser:	ARDECKY, ROBERT, JOHN, HASSIG, CHRISTIAN, A, PINKERTON, ANTHONY, B, PASS, IAN, JACKSON, MICHAEL, R
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of Glucocorticoid Receptor (GR) translocation. Furthermore, the subject compounds and compositions are useful for the treatment of diseases involved in the hypothalamic-pituitary-adrenal (HPA) axis. Cette invention concerne des composés de et des compositions pharmaceutiques les contenant. Les composés et compositions de l'invention sont utiles comme modulateurs de translocation du récepteurs des glucocorticoïdes (GR). En outre, les composés et compositions de l'invention sont utiles pour le traitement de maladies impliquant un dysfonctionnement de l'axe hypothalamo-pituito-surrénalien (HPS).