NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS

The invention relates to novel heteroaryl and heterocycle compounds of formula I and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI3K and for treating inflammatory and autoimmune diseases and cancer. La présente invention concerne de nouveaux...

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Hauptverfasser:	LEBSACK, ALEC DONALD, ECCLES, WENDY, DAI, GUANGXIU, CHAI, WENYING, MEDUNA, STEVEN PAUL, KEITH, JOHN MATTHEW, VENABLE, JENNIFER DIANE, WENG, JIANYANG, SMITH, RUSSELL CHRISTOPHER, JIA, HONG, ZHANG, ZHULIN, BEMBENEK, SCOTT DAMIAN, SU, WEI-GUO, JONES, WILLIAM MOORE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to novel heteroaryl and heterocycle compounds of formula I and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI3K and for treating inflammatory and autoimmune diseases and cancer. La présente invention concerne de nouveaux composés hétéroaryliques et hétérocycliques de formule I et des compositions pharmaceutiques comprenant ceux-ci, leurs utilisations et procédés pour inhiber l'activité de la PI3K et traiter des maladies inflammatoires et auto-immunes ainsi que le cancer.