DOSAGE REGIMEN FOR MADCAM ANTAGONISTS

The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided. La pré...

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Bibliographische Detailangaben
Hauptverfasser:	HASSAN-ZAHRAEE, Mina, ZHANG, Weidong, TILLEY, Mera Krishnan, PRADHAN, Vivekananda, COMER, Gail M, VINCENT, Michael Steven, BANERJEE, Anindita, CATALDI, Fabio, PAGE, Karen Michelle, AHMAD, Alaa, CLARE, Robert A, VON SCHACK, David J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided. La présente invention concerne une méthode pour le traitement d'un patient comprenant l'administration au patient d'une dose initiale comprise entre environ 1 mg et environ 150 mg d'un anticorps antagoniste de MAdCAM. L'invention concerne également des biomarqueurs pour évaluer la réponse d'un patient au traitement anti-MAdCAM.