NOVEL CALCIUM MODULATORS

Disclosed are novel calcium modulators having formula I: or a pharmaceutically acceptable salt, and including deuterated forms thereof, wherein: Z1, Z2, Z3, Z4 Z5, R1, R1', R2, R3, R3' R4, and R4', are as defined throughout the specification; pharmaceutical compositions thereof; and m...

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Bibliographische Detailangaben
Hauptverfasser: KELLY, MICHAEL, GERARD, KINCAID, JOHN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Disclosed are novel calcium modulators having formula I: or a pharmaceutically acceptable salt, and including deuterated forms thereof, wherein: Z1, Z2, Z3, Z4 Z5, R1, R1', R2, R3, R3' R4, and R4', are as defined throughout the specification; pharmaceutical compositions thereof; and methods of use thereof. L'invention concerne de nouveaux modulateurs du calcium ayant la formule I : ou un sel pharmaceutiquement acceptable, et incluant des formes deutérées de ceux-ci, Z1, Z2, Z3, Z4 Z5, R1, R1', R2, R3, R3' R4, et R4' étant tels que définis dans la description; des compositions pharmaceutiques de ceux-ci; et des procédés d'utilisation de ceux-ci.