THIOTRIAZOLE COMPOUND AND ITS USE IN PARASITIC PROTOZOAL INFECTIONS

The present invention relates to a compound of Formula (I) or tautomers thereof having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasitic protozoal infections such as malaria, in particular infect...

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Bibliographische Detailangaben
Hauptverfasser:	WILSON, DAVID MATTHEW, DIAZ HERNANDEZ, BEATRIZ, FERNANDEZ VELANDO, ESTHER PILAR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a compound of Formula (I) or tautomers thereof having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasitic protozoal infections such as malaria, in particular infection by Plasmodium falciparum. (R)-2-((3-(3,5-dichloropyridin-4-yl)-1H-1,2,4-triazol-5-yl)thio)-1-(1H-indol-3-yl)propan-1-one La présente invention concerne un composé de Formule (I) ou des tautomères de ceux-ci ayant une activité pharmacologique, des procédés pour sa préparation, des compositions pharmaceutiques et leur utilisation dans le traitement de certains certaines infections parasitaires causées par des protozoaires parasitaires telles que la malaria, en particulier une infection par Plasmodium falciparum. (R) -2- ((3- (3,5-dichloropyridin -4-yl) -1 H -1,2,4-triazol -5-yl) thio) -1- (1H-indol -3-yl) propan -1-one