PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS LENALIDOMIDE

The present invention relates to a pharmaceutical composition comprising an inclusion complex of amorphous lenalidomide, or a pharmaceutically acceptable salt thereof, in non-substituted β-cyclodextrin and one or more pharmaceutically acceptable excipients. The invention further relates to the use o...

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Bibliographische Detailangaben
Hauptverfasser:	MURPANI, DEEPAK, VIVANCOS MARTINEZ, MARTA, NOGUEIRAS NIETO, LUIS, KELTJENS, ROLF, ÁLVAREZ FERNÁNDEZ, LISARDO, EUPEN VAN, JACOBUS THEODORUS HENRICUS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical composition comprising an inclusion complex of amorphous lenalidomide, or a pharmaceutically acceptable salt thereof, in non-substituted β-cyclodextrin and one or more pharmaceutically acceptable excipients. The invention further relates to the use of said composition as a medicament, particularly in the treatment of in the treatment of multiple myeloma and myelodyplastic syndromes. La présente invention concerne une composition pharmaceutique comprenant un complexe d'inclusion de lénalidomide amorphe, ou son sel pharmaceutiquement acceptable dans une β-cyclodextrine non substituée, et un ou plusieurs excipients pharmaceutiquement acceptables. L'invention concerne en outre l'utilisation de cette composition en tant que médicament, notamment dans le traitement du myélome multiple et des syndromes myélodysplasiques.