USE OF AN ANTI-GM-CSF ANTAGONIST AND AN ANTI-CCR2 ANTAGONIST IN THE TREATMENT OF AN INFECTIOUS DISEASE

The present invention relates to combinations comprising anti-GM-CSF antagonists and anti- CCR2 antagonists in the treatment and prevention of infections caused by agents inducing hemorrhagic fever or in the modulation of an individual's immune or cellular response that has been exposed to, is...

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Bibliographische Detailangaben
Hauptverfasser:	ZALEVSKY, JONATHAN, SOUBERBIELLE, BERNARD
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to combinations comprising anti-GM-CSF antagonists and anti- CCR2 antagonists in the treatment and prevention of infections caused by agents inducing hemorrhagic fever or in the modulation of an individual's immune or cellular response that has been exposed to, is infected or suspected to be infected with such agents, e.g., Ebola viruses. L'invention concerne des combinaisons comprenant des antagonistes anti-GM-CSF et des antagonistes anti-CCR2 pour traiter et prévenir des infections provoquées par des agents induisant une fièvre hémorragique ou pour moduler la réponse cellulaire ou immunitaire d'un individu qui a été exposé, infecté ou susceptible d'être infecté par de tels agents, par exemple, le virus Ebola.