METHODS AND FORMULATION FOR IMPROVING ORAL AVAILABILITY OF CPT-11 WHILE REDUCING CPT-11 INDUCED GASTRONINTESTINAL TOXICITY IN CANCER THERAPY

Disclosed herein are methods and formulation for enhancing oral availability of CPT-11 during cancer therapy while at the same time, reducing its gastrointestinal (GI) toxicity, thus the methods and formulations as disclosed herein may augment the efficacy of cancer therapy. L'invention concern...

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Hauptverfasser: LIAO, PEI-RU, CHI, KUAN-HUA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Disclosed herein are methods and formulation for enhancing oral availability of CPT-11 during cancer therapy while at the same time, reducing its gastrointestinal (GI) toxicity, thus the methods and formulations as disclosed herein may augment the efficacy of cancer therapy. L'invention concerne des méthodes et une formulation pour améliorer la disponibilité orale de CPT-11 au cours du traitement du cancer tout en réduisant en même temps sa toxicité gastro-intestinale (GI), par conséquent, les méthodes et formulations selon la présente invention peuvent augmenter l'efficacité de la thérapie du cancer.