PROCESS FOR THE PREPARATION OF 4-[4-({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE AND ITS POLYMORPHS THEREOF

PROCESS FOR THE PREPARATION OF 4-[4-({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE AND ITS POLYMORPHS THEREOF

The present invention relates to a process for the preparation of 4-[4-({[4-chloro-3- (trifluoromethyl)phenyl]carbamoyl}amino)-3-fluophenoxy]-N-methylpyridine-2-caroxamide compound of formula- I, its amorphous form and its crystalline polymorph-I which is represented by the following structural form...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MADHUSUDHAN, GUTTA, THIRUMALAI RAJAN, SRINIVASAN, ESWARAIAH, SAJJA
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to a process for the preparation of 4-[4-({[4-chloro-3- (trifluoromethyl)phenyl]carbamoyl}amino)-3-fluophenoxy]-N-methylpyridine-2-caroxamide compound of formula- I, its amorphous form and its crystalline polymorph-I which is represented by the following structural formula: (I) La présente invention concerne un procédé permettant de préparer le 4-[4-({[4-chloro-3-(trifluorométhyl)phényl]carbamoyl}amino)-3-fluorophénoxy]-N-méthylpyridine-2-carboxamide de formule I, sa forme amorphe et sa forme polymorphe cristalline-I qui est représentée par la formule structurelle suivante : (I)